Scientists Focus on the cause of prostate cancer

Reading Always - Today update article about Scientists Focus on the cause of prostate cancer. Read an article today update, The prostate is a gland in the male sex organs. Prostate cancer occurs when cells in the prostate mutate and begin to multiply out of control. The peripheral zone of prostate cancer usually develops first. These small groups of cancer cells to keep otherwise healthy prostate. As long as the cells begin to multiply, which can spread into the surrounding prostate tissue. Finally, a tumor that can invade nearby organs such as the seminal vesicles, bladder or rectum. Or tumor cells in lymph nodes and blood vessels. People with prostate cancer often have no symptoms. Other symptoms similar to those found with BPH, such as sexual dysfunction.


In search of a cure for prostate cancer researchers have focused on "androgen receptors". Androgens are hormones (like testosterone) that are important for normal male sexual development before birth and during puberty. The androgen receptor allows the body to respond to these hormones. Typical applications include drugs, cancer, androgen production slowly.But according to the researchers, this type of treatment is usually less effective over time, since the resistance of cancer cells grew and multiplied.

This is good news after reading cutting edge research conducted at the Michigan Center for Translational Pathology. There, scientists believe they have discovered the main cause of prostate cancer - and has very little to do with the androgen receptor. The most common cause of cancer could, in fact, the fusion of two genes. When these two genes fuse, which is the basis for the abnormal growth of prostate cells.The research team compared the gene fusion have a power switch for the development of prostate cancer. It causes cancer begins with the fusion gene with a first prostate cancer gene. The researchers were able to use high-tech genetic mapping techniques to discover that once the merger takes place, androgen receptors are blocked, which in turn reduce the normal growth of prostate cancer cells, while the differentials.

The research team concluded that their study shows that the underlying problem in the presence of gene fusion prostate cancer, not the androgen receptor. In some contexts, androgen signaling is actually a good thing, but the presence of the fusion of the androgen receptor gene. This in turn alters the normal growth of prostate cells.

It will be interesting to see if scientists can use this discovery to go forward and find a cure for prostate cancer. Perhaps there is a chance you happen to stop the fusion gene, in order to protect the health of the genes in prostate cancer-causing genes. And if this can be found for cancer, maybe it could provide information about how to prevent other cancers.